The Era of Quantifiable Beauty Has Arrived

Vascular Permeability Increase and Inflammatory Cell Infiltration

• What is Vascular Permeability?

  This refers to the movement of water, nutrients, and other substances between blood vessels and surrounding tissues. When vascular permeability increases, relatively large proteins that normally cannot pass through can move across blood vessels.

• What is Inflammatory Cell Infiltration?

  This is the state where inflammatory cells gather at the site of inflammation as part of the body's defense response. Inflammatory cells play multiple roles in the body, such as destroying and removing pathogens, or signaling other inflammatory cells to respond and helping the body remember pathogens for faster future responses.

Four Key Features

Cell Proliferation and Differentiation

Promotes tissue and organ formation and repair by stimulating cell proliferation and differentiation.

Angiogenesis

A physiological process where new blood vessels form. Promotes endothelial cell proliferation and angiogenesis, increasing tissue oxygen and nutrient supply.

Neural Protection and Regeneration

Promotes neural development by stimulating the growth and differentiation of nerve cells.

Bone Formation

Enhances bone formation by promoting the growth and differentiation of osteoblasts***, which are precursor cells to bone cells. This can increase bone density and facilitate bone formation.

Promotion of Angiogenesis

Enhanced Bactericidal Effects

Four Key Features

• Cell Proliferation and Differentiation

  Has proliferation and differentiation-promoting effects on many cell types.

  

• Angiogenesis

  Promotes blood vessel formation by enhancing the expression of angiopoietin (a protein crucial for angiogenesis).

  

• Cell Regeneration Promotion

  Promotes regeneration of cells and tissues damaged by injury or inflammation.

  

• Anti-fibrotic Effect

  Suppresses fibroblast* proliferation and prevents liver fibrosis** and other organ fibrosis. HGF plays particularly important roles in organs such as the liver, kidneys, and lungs.

  

Five Key Features

• Skin Cell Proliferation

  Plays a crucial role in cell proliferation. Promotes skin cell growth and improves sagging and wrinkles.

• Wound Healing

  Effective in wound healing. Useful for skin regeneration after burns or surgery.

• Beauty Effects

  Enhances skin cell moisture retention and improves texture for beauty benefits.

• Antioxidant Action

  Possesses antioxidant properties that help prevent skin cell aging.

• Blood Circulation Promotion

  Improves skin blood circulation. Better blood flow supplies necessary nutrients and oxygen to skin cells, maintaining healthy skin.

Main Characteristics of NGF

• Promotes Neural Cell Differentiation and Growth

  Functions to maintain neural cell features and morphology by providing survival support necessary for neural cell growth.

• Promotes Neural Regeneration

  When NGF acts on neural cells, it can support neural regeneration at damaged sites in neural circuits.

• Contributes to Cognitive Function Improvement

  Improves cognitive function by regulating neurotransmitter balance in the brain and preventing neuron death. Research has shown that directly injecting NGF into the brain to stimulate NGF receptors increases cerebral blood flow and improves episodic memory.

• Treats Neurological Disorders

  Shows potential for treating neurological conditions such as Alzheimer's disease, Parkinson's disease, neuralgia, epilepsy, and motor neuron diseases.